The Salary Index
Salary data is based on the Appleton, WI metropolitan area and applied to Appleton using local cost-of-living adjustments.

Physician Assistants Salaries in Appleton, WI

Average Base Pay

$125,119/yr

7% below national average

Monthly

$10,427

Hourly

$60

Cost Index

86

Physician Assistants in Appleton, WI earn an average of $125,119 per year, with most salaries falling between $100,095 and $150,143 depending on experience, employer, and specialization. At 7% below the national average, Appleton offers a more modest rate for this role, in part reflecting a local cost of living index of 86. For professionals evaluating a move or negotiating an offer, the headline salary is only part of the picture—what matters most is how far that income actually goes once taxes, rent, and daily expenses are factored in. The sections below break that down in full for Appleton.

Salary Range

The chart below shows the full compensation spectrum for this role, from entry-level to senior positions. The highlighted center bars represent the 25th–75th percentile band where most professionals are paid.

$94K
Low
$125K
Median
$156K
High
25th percentile: $106K75th percentile: $144K

About Physician Assistants

Physician Assistants are licensed medical professionals who practice medicine under the supervision of physicians. They examine patients, diagnose illnesses, develop and manage treatment plans, prescribe medications, and assist in surgery. PAs work across virtually every medical specialty—primary care, surgery, emergency medicine, orthopedics, psychiatry, and more—and their scope of practice varies by state law and practice agreement. In primary care settings, PAs conduct routine physical exams, diagnose common illnesses, manage chronic conditions such as diabetes and hypertension, and counsel patients on preventive health. In surgical settings, they assist in operations, manage pre- and post-operative care, and perform procedures such as suturing and casting. PAs adapt their approach across patient populations from pediatrics to geriatrics. The role requires a master's degree from an accredited PA program, which includes extensive clinical rotations, followed by passing the PANCE examination. PAs must maintain their certification through continuing medical education and pass recertification exams periodically. The profession is growing rapidly as demand for healthcare services increases and PAs help extend the capacity of physician-led teams.

What Physician Assistants Do

  • Conduct patient history and physical examinations
  • Diagnose acute and chronic medical conditions
  • Develop and manage individualized treatment plans
  • Prescribe medications and therapies within scope of practice
  • Order and interpret diagnostic tests including labs and imaging
  • Assist in surgical procedures and manage perioperative care
  • Educate patients on diagnoses, treatment options, and lifestyle modifications
  • Collaborate with supervising physicians and the broader care team

Key Skills & Qualifications

  • Clinical assessment and differential diagnosis
  • Procedural skills appropriate to specialty (suturing, joint injections, casting)
  • Pharmacology and medication prescribing
  • Interpretation of lab results and medical imaging
  • Electronic health record documentation
  • Patient communication and shared decision-making
  • PANCE certification and ongoing CME requirements
  • Ability to work effectively in high-volume, time-pressured clinical environments

Career Path

  1. Medical Assistant / EMT (pre-PA experience)
  2. Physician Assistant
  3. Senior PA / Lead PA
  4. PA Supervisor / Clinical Coordinator
  5. Healthcare Administrator / Program Director

Physician Assistants Market in Appleton, WI

Salary Competitiveness

Appleton currently pays 7% below the national median for Physician Assistants. This gap can reflect a lower regional cost base, thinner employer density, or a surplus of qualified candidates relative to open roles—factors worth factoring into any offer negotiation or relocation calculation.

Cost of Living Impact

Appleton's cost of living runs below the national average, which works in favor of this salary. Essential monthly expenses account for approximately 29% of take-home pay—a ratio that leaves meaningful room for savings, debt reduction, and discretionary spending compared with higher-cost metros.

Effective Purchasing Power

After adjusting for local taxes and cost of living, a Physician Assistants earning $125,119 in Appleton reaches a strong purchasing-power position. The effective standard of living this income supports is materially higher than the gross number alone implies—a useful data point for professionals comparing offers across metro areas.

vs. National Avg

-7%

Cost Pressure

29%

Purchasing Power

Strong

Take-Home Pay Calculator

Enter any gross salary to see how federal and state taxes affect your actual take-home pay, broken down by year, month, and week. Results use an estimated effective tax rate of 27% based on this location and income level.

$
Take-home (73%)Taxes (27%)

Annual Net

$91,337

Monthly

$7,611

Weekly

$1,756

Eff. Tax Rate

27%

A gross salary of $125,119 for a Physician Assistants in Appleton translates to roughly $7,611 in monthly take-home pay after estimated federal and state taxes. Set against monthly living costs of $2,227—covering housing, food, transportation, utilities, and healthcare—that leaves approximately $5,384 per month in disposable income. That margin, not the gross number, is what determines whether you can comfortably cover rent, build savings, and afford discretionary spending in Appleton's current market.

How far does this salary go in Appleton?

Cost of Living in Appleton

Estimated monthly expenses for a single person in Appleton, benchmarked against US regional price indices for housing, food, transportation, utilities, and healthcare.

Cost Index

86

Below Avg — US average is 100. Based on a single person (1-bed apartment).

🏠Housing / Rent$1,281/mo
🍔Food & Groceries$427/mo
🚗Transportation$115/mo
💡Utilities$150/mo
🏥Healthcare$254/mo
Monthly$2,227
Annual$26,724
Disposable Income$5,384

Financial Reality Check

This section compares estimated monthly take-home pay against typical living costs in Appleton to show your real disposable income—the amount remaining after essential bills are paid each month.

Monthly Take-Home

$7,611

Living Costs

$2,227

Disposable

$5,384

Cost Index

86

Lifestyle

Comfortable

With a monthly take-home of $7,611, your estimated living costs in Appleton are $2,227 ($26,724/yr). This leaves $5,384 per month in disposable income, indicating a comfortable standard of living. Appleton's cost of living is 14% below the national average.

Overall, a Physician Assistants earning $125,119 in Appleton falls into a comfortable lifestyle tier and has meaningful room to save, invest, and absorb unexpected expenses without financial stress. With a cost index of 86, Appleton is 14% more affordable than the national average, which extends your purchasing power. Regardless of tier, prioritizing retirement contributions, an emergency fund of three to six months' expenses, and incremental debt reduction will yield the greatest long-term financial stability—especially as living costs in Appleton continue to evolve.

Frequently Asked Questions

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Physician Assistants · Appleton, WI7% below avg

Gross Salary

$125,119/yr

Take-home

$7,611/mo

Disposable

$5,384/mo

Lifestyle

Comfortable

Source: thesalaryindex.com · BLS data

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Salary estimates are based on BLS metro data and adjusted using cost-of-living indices.